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	<title>Baby, Pregnancy, and Parenting at Babies Online &#187; cancer</title>
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		<title>Questions To Ask When Considering Cord Blood Preservation For Your Baby</title>
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		<pubDate>Sun, 09 Mar 2008 18:28:36 +0000</pubDate>
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		<guid isPermaLink="false">http://208.79.203.56/articles/pregnancy/cordblood.asp</guid>
		<description><![CDATA[By Brent N. Davidson, M.D. Congratulations on the upcoming birth of your baby. It’s an exciting time and you probably have a lot on your mind anticipating the arrival of your new baby. It’s also a time that presents an opportunity to do something extraordinary for your baby and your family – the opportunity to [...]]]></description>
			<content:encoded><![CDATA[<p><em>By Brent N. Davidson, M.D.</em></p>
<p align="justify"><a href="http://www.babiesonline.com/articles/wp-content/uploads/2009/02/questions-to-ask-when-considering-cord-blood-preservation-for-your-baby.jpg"><img class="alignright size-full wp-image-3375" style="float: right; margin: 5px; border: 0px;" title="Questions To Ask When Considering Cord Blood Preservation" src="http://www.babiesonline.com/articles/wp-content/uploads/2009/02/questions-to-ask-when-considering-cord-blood-preservation-for-your-baby.jpg" alt="" width="230" height="153" /></a>Congratulations on the upcoming birth of your baby. It’s an exciting time and you probably have a lot on your mind anticipating the arrival of your new baby. It’s also a time that presents an opportunity to do something extraordinary for your baby and your family – the opportunity to preserve your newborn’s cord blood stem cells.</p>
<p align="justify">Currently, the stem cells in your baby’s cord blood can be used in the treatment of over 70 chronic or life-threatening diseases. Diseases like Leukemia and other cancers, genetic and blood diseases, and a range of immune system deficiencies. Plus, researchers are now looking to cord blood for answers to heart disease, stroke, diabetes and muscular dystrophy.</p>
<p align="justify">You only get one chance to preserve your baby’s cord blood. That’s why it’s critical to select a high quality cord blood company. Here are key questions to ask before selecting a cord blood company:</p>
<ol>
<li><strong>Is the company accredited by The American Association of Blood Banks (AABB)?</strong>
<p align="justify">Make sure the cord blood banking company you are considering is fully accredited by the American Association of Blood Banks (AABB) specifically for the processing of cord blood stem cells. The AABB is the only accreditation that ensures high standards of quality for the processing and storage of your baby’s cord blood.</p>
<p align="justify">Some banks are fee-paying members of the AABB, but that’s not the same as being fully accredited. To be accredited, the cord blood banking company must have its laboratory and administrative procedures reviewed, inspected and validated regularly and their procedures must be compliant with the guidelines established by AABB for cord blood processing.</p>
<p align="justify">It’s even better if the cord blood banking company you select is recognized by AABB as having procedures that represent exceptional and novel practices in the industry.</p>
</li>
<li><strong>How experienced is the cord blood banking company and do they guarantee their product?</strong>
<p align="justify">You should ask the company you’re considering how many cord blood units they have stored, and whether they have facilitated any successful transplants.</p>
<p align="justify">You should be cautious of a company that has a high number of cord blood units collected and stored, but has never or rarely used a unit for transplant. It could mean transplant physicians have rejected their cord blood – a warning flag that the company’s procedures are not thorough.</p>
<p align="justify">Best of all is if the company offers a quality product guarantee. This ensures the fact that you are dealing with a quality-conscious company dedicated to providing the highest quality processing and cryopreservation of your baby’s cord blood.</p>
</li>
<li><strong>Is the company financially stable?</strong>
<p align="justify">Cord blood banking is a costly industry. Some companies have gone out of business and parents actually have lost their cord blood units. Assessing a company’s long-term financial future is difficult, however there are a few critical questions you should ask. The first is, what the company would do with your cord blood if they were to go out of business. Be sure the company you are considering has a reasonable plan to accommodate customers, such as a formal written agreement with another medical facility where they would take over the management of the cord blood units.</p>
<p align="justify">You should also ask how long the company has been preserving cord blood. In addition, you should find out if the company is a division of larger corporation, and whether there are academic affiliations, research collaborations and equity partnerships with major biotechnology companies. This would provide proof that the company is committed to researching and developing further applications for cord blood stem cell therapy and will most likely be around for the long term.</p>
</li>
<li><strong>Does their service include bedside pick up by a Private Medical Courier and do they employ state-of-the-art tracking technology to ensure timely delivery?</strong>
<p align="justify">Look for a company that handles the logistics and uses a private medical courier to ensure the quickest, highest quality pick-up and delivery of your baby’s cord blood. The company should arrange to pick up your baby’s cord blood from your bedside in the hospital and transport it to the laboratory 24-hours a day, any day of the week, weekend or holiday. The company should manage all courier and transportation logistics, including accurate tracking of sample handling, and should be committed to transporting the cord blood unit to the laboratory within 24 hours of the baby’s birth to ensure maximum viability.</p>
<p align="justify">The three areas proven to increase and maintain cell viability are timing, pressure and temperature regulation, all of which are controlled by the use of a private medical courier. This ensures the cord blood unit is kept at the proper temperature and pressure during transport and ensures the cord blood unit it delivered to the laboratory within 24 hours. With a private medical courier, your child’s cord blood gets to the lab quickly and safely while avoiding the potentially damaging temperature swings and pressure changes that happen with standard package carriers. This maximizes the number of cells that can be used in a transplant should you ever need them.</p>
</li>
<li><strong>How does the company collect and store your child’s cord blood?</strong>
<p align="justify">Look for a company that uses the Gravity Bag Collection method (vs. Syringe method). The Gravity Bag is the collection method most preferred by doctors and it is designed to collect the greatest volume of cord blood. It’s the industry standard method used by the majority of blood banks and similar to the methods used by the American Red Cross and the National Institutes of Health. It is important to collect as much cord blood as possible, as results show that larger samples produce more viable stem cells. The Gravity Bag method allows for the most cord blood to flow into the bag. In addition, the closed tube/bag system eliminates exposure to airborne bacteria and greatly reduces likelihood of contamination during collection. Be sure the company you are looking at provides a sterile collection protocol to allow for collections to be performed during C-sections and emergency births.</p>
<p align="justify">Look at how the company stores the cord blood after processing. Look for a company that cryopreserves the processed cord blood in multi-compartment, transplant-ready Cryobags. Cryobags allow for higher cell recovery rates and a higher cell viability rate compared to other storage methods like Cryovials. While storage in Cryovials is less expensive for cord blood companies, it does not maximize the value of the stem cells for families. The superiority of the Cryobags allow for higher cell recovery and higher viability than Cryovials.</p>
<p align="justify">Additionally, the company should store a small amount of processed cord blood in aliquots – a small compartment of cord blood designed for pre-transplantation testing. The benefit is that the testing can be done without disturbing the primary compartments. With the Cryovial method, an entire vial must be thawed and used to perform this necessary pre-transplantation testing procedure.</p>
</li>
<li><strong>Does the company have a Medical Scientific Advisory Board (MSAB) made up of notable authorities in the field of cord blood stem cell preservation and transplantation?</strong>
<p align="justify">The company you are considering should have a Medical Scientific Advisory Board (MSAB) made up of thought leaders in the field of stem cell transplantation and cord blood preservation. Ask how the company uses their MSAB. They should meet regularly to set quality standards within the company and thereby help to maintain the highest and most advanced level of service available.</p>
</li>
<li><strong>Is the company committed to research for future applications of cord blood?</strong>
<p align="justify">Look for a company that actively participates and invests in research and development of cord blood stem cell therapies. If a cord blood company is committed to research, it’s a good indication that the company is also committed to the future, which means they are more likely to have financial stability. Another potential benefit &#8212; any medical breakthroughs developed by their R&amp;D division will have been conducted using their own processing and cryopreservation methodology. In other words, you may be in a better position to benefit from their discoveries by using their processing techniques as opposed to methods used by other cord blood companies.</p>
</li>
</ol>
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		<title>Women and Nutrition: A Menu of Special Needs</title>
		<link>http://www.babiesonline.com/articles/women/womennutrition.asp</link>
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		<pubDate>Thu, 28 Feb 2008 16:18:44 +0000</pubDate>
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				<category><![CDATA[Women]]></category>
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		<guid isPermaLink="false">http://208.79.203.56/articles/women/womennutrition.asp</guid>
		<description><![CDATA[By Dori StehlinBreast cancer. Osteoporosis. Iron deficiency. Weight reduction. What do these things have in common? They are either unique to women, or are more prevalent in women. And they affect current recommendations on what women should eat for optimum health. While new information on what&#8217;s good and what&#8217;s bad seems to surface almost daily, [...]]]></description>
			<content:encoded><![CDATA[<p><em>By Dori Stehlin</em>Breast cancer. Osteoporosis. Iron deficiency. Weight reduction. What do these things have in common? They are either unique to women, or are more prevalent in women. And they affect current recommendations on what women should eat for optimum health.</p>
<p>While new information on what&#8217;s good and what&#8217;s bad seems to surface almost daily, some basic guidelines have taken root over the past several years.</p>
<p>The bottom line (also known as the Dietary Guidelines for Americans, from the Departments of Health and Human Services and Agriculture) is:</p>
<li>eat a variety of foods</li>
<li>maintain healthy weight</li>
<li>choose a diet low in fat, saturated fat, and cholesterol</li>
<li>choose a diet with plenty of vegetables, fruits, and grain products</li>
<li>use sugar and salt/sodium only in moderation</li>
<li>if you drink alcoholic beverages, do so in moderation.That sounds simple enough. Except, what exactly is variety? Cake one day, cookies the next? What is a diet low in fat, saturated fat, and cholesterol? And, finally, what parts of a healthy diet have special importance for women?<strong>Vitamins and Minerals<br />
</strong>There are several vitamins and minerals essential to a healthy diet. A well-balanced diet will usually meet women&#8217;s allowances for them. (See Recommended Dietary Allowances.) However, for good health, women need to pay special attention to two minerals, calcium and iron.</p>
<p><strong>Calcium<br />
</strong>Both women and men need enough calcium to build peak (maximum) bone mass during their early years of life. Low calcium intake appears to be one important factor in the development of osteoporosis. Women have a greater risk than men of developing osteoporosis.</p>
<p>A condition in which progressive loss of bone mass occurs with aging, osteoporosis causes the bones to be more susceptible to fracture. If a woman has a high level of bone mass when her skeleton matures, this may modify her risk of developing osteoporosis.</p>
<p>Therefore, particularly during adolescence and early adulthood, women should increase their food sources of calcium. &#8220;The most important time to get a sufficient amount of calcium is while bone growth and consolidation are occurring, a period that continues until approximately age 30 to 35,&#8221; says Marilyn Stephenson, a registered dietitian with FDA&#8217;s Center for Food Safety and Applied Nutrition. &#8220;The idea is, if you can build a maximum peak of calcium deposits early on, this may delay fractures that occur later in life.&#8221;</p>
<p>The recommended dietary allowance (RDA) for calcium for woman 19 to 24 is 1,200 milligrams per day. For women 25 and older, the allowance drops to 800 milligrams, but that is still a significant amount, says Stephenson. &#8220;The need for good dietary sources of calcium continues throughout life,&#8221; she says.</p>
<p>How do you get enough calcium without too many calories and fat? After all, the foods that top the calcium charts&#8211;milk, cheese, ice cream&#8211;aren&#8217;t calorie and fat lightweights.</p>
<p>&#8220;There are lots of lower fat choices,&#8221; says Stephenson. &#8220;There&#8217;s 1 percent or skim milk instead of whole milk. There&#8217;s a good variety of lower fat cheeses, yogurts, and frozen yogurts, and there&#8217;s a whole flock of substitutes for ice cream.&#8221;</p>
<p>In addition to dairy foods, other good sources of calcium include salmon, tofu (soybean curd), certain vegetables (for example, broccoli), legumes (peas and beans), calcium-enriched grain products, lime-processed tortillas, seeds, and nuts.</p>
<p><strong>Iron<br />
</strong>For women, the RDA for iron is 15 milligrams per day, 5 milligrams more than the RDA for men. Women need more of this mineral because they lose an average of 15 to 20 milligrams of iron each month during menstruation. Without enough iron, iron deficiency anemia can develop and cause symptoms that include pallor, fatigue and headaches.</p>
<p>After menopause, body iron stores generally begin to increase. Therefore, iron deficiency in women over 50 may indicate blood loss from another source, and should be checked by a physician.</p>
<p>Animal products&#8211;meat, fish and poultry&#8211;are good and important sources of iron. In addition, the type of iron, known as heme iron, in these foods is well absorbed in the human intestine.</p>
<p>Dietary iron from plant sources, called non-heme, are found in peas and beans, spinach and other green leafy vegetables, potatoes, and whole-grain and iron-fortified cereal products. Although non-heme iron is not as well absorbed as heme iron, the amount of non-heme iron absorbed from a meal is influenced by other constituents in the diet. The addition of even relatively small amounts of meat or foods containing vitamin C substantially increases the total amount of iron absorbed from the entire meal.</p>
<p><strong>Calories and Weight Control</strong><br />
The Food and Nutrition Board of the National Research Council recommends that the average woman between 23 and 50 eat about 2,200 calories a day to maintain weight. (Chart of Suggested Weights for Adults)</p>
<p>The best way for a woman to determine whether she&#8217;s eating the right number of calories is to &#8220;keep stepping on the scale,&#8221; says FDA&#8217;s Stephenson.</p>
<p>She cautions, however, that cutting back on calories isn&#8217;t always the answer to losing weight. &#8220;You don&#8217;t really want to cut back any more [calories] if you&#8217;re down around that [1,500 calories] range,&#8221; says Stephenson. She explains that the fewer the calories you have to work with, the harder it is to meet all your daily requirements for a healthy diet.</p>
<p>&#8220;If you find you are gaining weight, you need to think of not only cutting calories, but also about increasing exercise,&#8221; she says. &#8220;Calories are only half the equation for weight control. Physical activity burns calories, increases the proportion of lean to fat body mass, and raises your metabolism. So, a combination of both calorie control and increased physical activity is important for attaining healthy weight.</p>
<p>&#8220;On the other hand, if you&#8217;ve been pigging out&#8211;well, you know what you have to do.&#8221;</p>
<p><strong>Cholesterol</strong><br />
Women tend to have higher levels than men of a desirable type of cholesterol called HDLs (high-density lipoproteins) until menopause, leading some researchers to believe there is a link between HDLs and estrogen levels. But this doesn&#8217;t let women off the hook&#8211;a diet high in saturated fat and cholesterol can still mean trouble.</p>
<p>For both women and men, blood cholesterol levels of below 200 milligrams are desirable. Levels between 200 and 239 milligrams are considered borderline and anything over 240 milligrams is high. High levels of blood cholesterol increase the risk of coronary heart disease.</p>
<p>To keep levels in the good range, the National Cholesterol Education Program of the National Heart, Lung, and Blood Institute recommends eating no more than 300 milligrams of cholesterol a day. Cholesterol is found only in food from animal sources, such as egg yolks, dairy products, meat, poultry, shellfish, and&#8211;in smaller amounts&#8211;fish and some processed products containing animal foods.</p>
<p>Even more important than limiting cholesterol to less than 300 milligrams is keeping saturated fat lass than 10 percent of total calories, says Nancy Ernst, the nutrition coordinator for the National Heart, Lung, and Blood Institute.</p>
<p>&#8220;Don&#8217;t even think about cholesterol in your diet,&#8221; says Ernst. &#8220;Focus on reducing saturated fat.&#8221;</p>
<p><strong>Fat<br />
</strong>In the United States, out of every 100,000 women, approximately 27 die from breast cancer each year. In Japan, breast cancer deaths are fewer than 7 per 100,000. Some scientists think that the difference in death rates may be related to the different amounts of fat in the average diet in each country&#8211;40 percent for American women versus 20 percent in Japan.</p>
<p>&#8220;We believe pretty strongly in the link [between high-fat diets and breast cancer],&#8221; says Jeffrey McKenna, director of NCI&#8217;s Cancer Awareness Program.</p>
<p>Population studies have also linked high-fat diets to other cancers, particularly colorectal cancer.</p>
<p>Fat does, however, serve a purpose in the diet. Fats in foods provide energy and help the body absorb certain vitamins. But it is as easy as pie (and doughnuts, ice cream, and sirloin steaks) to eat too much.</p>
<p>For a healthy diet, the diet and health report of the National Research Council recommends reducing fat to no more than 30 percent of total calories. (Figure out your fat intake.) But that&#8217;s not all. In terms of heart disease, the kinds of fat you eat are as important as how much.</p>
<p>There are three kinds of fat&#8211;saturated, polyunsaturated and monounsaturated. All three are equal when it comes to calories&#8211;9 per gram (compared to 4 calories per gram for protein or carbohydrate). But they aren&#8217;t equal when it comes to how they affect your health.</p>
<p>More than anything else in the diet, saturated fat can raise your blood cholesterol level. Because of this risk, less than one-third of your daily fat intake (less than 10 percent of total calories) should come from saturated fats.</p>
<p>That&#8217;s the bad news. The good news is polyunsaturated and monounsaturated may actually lower blood cholesterol levels. The diet and health report recommends that not more than 10 percent of total calories should be from polyunsaturated fat, and monounsaturated fat should make up the remaining 10 percent.</p>
<p>The foods with the highest amounts of saturated fat come from animals&#8211;meat, of course, and foods derived from animals, such as butter, cream, ice cream, and cheese. In addition to animal products, coconut and palm kernel oils are very high in saturated fat&#8211;over 90 percent.</p>
<p>The best sources for polyunsaturated fats are plant-based oils&#8211;sunflower, corn, soybean, cottonseed, and safflower. Monounsaturated fats are found in the largest amounts in olive, canola and peanut oils.</p>
<p><strong>Fiber<br />
</strong>An apple a day&#8211;that is, a whole apple with the skin&#8211;will give you approximately 3.6 grams of fiber. That&#8217;s a good start, but you still need a lot more fruits, vegetables, and whole grains to meet the daily level of 20 to 30 grams of fiber recommended by the National Cancer Institute.</p>
<p>Eating foods with plenty of complex carbohydrates and fiber (vegetables, fruits, and grain products) is part of a healthy diet for several reasons. A fiber-rich diet is helpful in the management of constipation and may be related to lower rates of colon cancer. These types of foods are generally low in fat and can be substitutes for fatty foods.</p>
<p>Fiber comes in two forms&#8211;insoluble and soluble. Insoluble fiber, mostly found in whole-grain products, vegetables and fruit, provides bulk for stool formation and helps move wastes more quickly through the colon. Another benefit is the full feeling fiber may create in the stomach, a possible deterrent to overeating.</p>
<p>Soluble fiber has been linked to lowering blood cholesterol levels, but that&#8217;s still a research area according to the Surgeon General&#8217;s Report on Nutrition and Health. There are many sources of soluble fiber, including peas and beans, many vegetables and fruits, and rice, corn and oat bran. There are even small amounts in pasta, crackers, and other bakery products.</p>
<p>Although foods containing fiber seem to exert a protective effect against some cancers, the diet and health report points out there is no conclusive evidence that dietary fiber itself, rather than other components, exerts this effect. Therefore, the report does not recommend the use of fiber supplements.</p>
<p>As important as fiber is to good health, it can be overdone. NCI recommends an upper limit of 35 grams a day. More probably won&#8217;t further increase the benefits from fiber, and may interfere with the body&#8217;s ability to absorb iron and other minerals.</p>
<p>When increasing the amount of fiber in your diet, do it slowly, so your body can become accustomed to handling it. Adding too much fiber too quickly may lead to uncomfortable side effects, including abdominal discomfort, flatulence and diarrhea.</p>
<p><strong>Food Preparation<br />
</strong>Carefully selecting foods for a well-balanced diet can end up a wasted effort if equal care isn&#8217;t used in the kitchen. Some important points to help make the most of healthy food: To help reduce fat, broil, bake or microwave food rather than frying or deep-fat frying. Cook vegetables in as little water as possible, or, instead of boiling food, try steaming. The steamer basket keeps the food above the water so the nutrients can&#8217;t be washed away. Also, heat can destroy some nutrients, so don&#8217;t overcook. Use fresh foods as soon as possible to avoid loss of vitamins. Season vegetables with herbs and spices instead of high-fat sauces, butter or margarine. Try lemon juice as a salad dressing. Substitute plain low-fat yogurt, blender-whipped low-fat cottage cheese, or buttermilk in recipes that call for sour cream or mayonnaise. Use skim or low-fat milk in place of whole milk in puddings, soups, and baked products.</p>
<p><strong>Getting a Variety of Foods</strong><br />
The Dietary Guidelines say that the many nutrients you need should come from a variety of foods, not from a few highly fortified foods or supplements. A good way to ensure variety is to choose foods each day from the five major food groups. USDA has developed a daily food guide for a well-balanced diet that suggests the following:</li>
<li>Vegetables &#8211; 3 to 5 servings</li>
<li>Fruits &#8211; 2 to 4 servings</li>
<li>Breads, cereals, rice, pasta &#8211; 6 to 11 servings</li>
<li>Milk, yogurt, cheese &#8211; 2 to 3 servings</li>
<li>Meat, poultry, fish, dried beans and peas, eggs, nuts &#8211; 2 to 3 servingsThis food guide is &#8220;a useful, simple way for women to look at their own diets and see how to improve them,&#8221; says Stephenson. By choosing different foods from each group daily, the food guide can serve as the basis for the dietary guideline &#8220;eat a variety of foods,&#8221; says Stephenson, and &#8220;that&#8217;s a tenet of nutritional advice for all people.&#8221; Finally, the guidelines are meant for the average person, cautions Walter H. Glinsmann, M.D., FDA&#8217;s associate director for clinical nutrition. &#8220;Almost nobody is average,&#8221; he says. Lifestyle, genetics, and conditions such as pregnancy or disease can also affect a person&#8217;s nutritional needs, he explains.<em><strong>About the Author<br />
</strong>Dori Stehlin is a staff writer for FDA Consumer. </em></li>
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